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Evidence · Efficacy · Safety

The science of precision nutrition

Across fifteen core areas of medical nutrition, AGX turns peer-reviewed research into actionable protocols — every mechanism explained, every active dosed, every claim PubMed-searchable.

Protecting cardiovascular health across the whole of life 01
Cardiovascular Health
Protecting cardiovascular health across the whole of life
Building a closed loop of precision cardiovascular nutrition — so every heart is guarded by science.
−19.5%Triglycerides
+29.5%Large-vessel function
−43%CV mortality risk

Why it matters

Vascular disease is the leading cause of death and disability worldwide. Global cardiovascular patients now number 626 million, with nearly 19.2 million deaths each year — roughly 32% of all deaths. Dyslipidemia, arterial stiffening, blood-pressure swings, cardiac load, thrombosis risk and microcirculation disorders compound into an all-ages threat.

Four-dimensional mechanism

  • Lipid control & vessel cleansing — clears and stabilises lipids, protects vascular endothelium.
  • Vascular elasticity & anti-stiffening — antioxidant defence, endothelial repair, improved microcirculation.
  • Cardiac power & circulation — boosts myocardial efficiency, protects cardiomyocytes, enhances mitochondrial function.
  • Thrombosis & anticoagulant care — maintains normal clotting balance and promotes fibrinolysis.

Core actives

Red yeast rice extract, reduced-form Coenzyme Q10 (ubiquinol), curcumin, PQQ, nattokinase.

Clinical results

  • Significant lipid improvement in 8–12 weeks: TG −19.5%, TC −11.4%, LDL-C −14.6%, HDL-C +16.1%, DBP −8.67%
  • Vascular function: large-vessel +29.5%, microvascular +37%
  • Cardiac energy metabolism: relative CV mortality risk −43%, heart-failure hospitalisation −50%, 6-minute walk +31.7 m
  • Fibrinolysis: D-dimer +44.5% at 6 h post-nattokinase

Featured product: OverTop Arctic Seal Oil. References on file; figures reflect published research on the named actives at studied doses.

Science that protects joints and bone — restoring every flex 02
Joint & Bone Care
Science that protects joints and bone — restoring every flex
Repairing cartilage, calming inflammation, restoring lubrication and rebuilding joint vitality through precision, evidence-based nutrition.
+23.6%Cartilage thickness
−53.6%Synovitis area
−48.7%VAS pain

Why it matters

Joints are the body's movement hub. Per The Lancet Rheumatology, more than 500 million people live with osteoarthritis, and knee-OA prevalence reaches 22.9% in adults over 40. AGX rejects surface-level pain masking and targets the real roots — cartilage wear, inflammatory factors, reduced synovial fluid and oxidative damage.

Core mechanism

  • Cartilage repair & regeneration — type-II collagen, chondroitin and glucosamine stimulate matrix synthesis.
  • Anti-inflammation & analgesia — boswellic acid, MSM and eggshell-membrane extract suppress the NF-κB pathway.
  • Lubrication & cushioning — promotes hyaluronic-acid production to reduce friction.
  • Anti-oxidation & anti-degradation — scavenges free radicals, inhibits MMPs to protect cartilage integrity.

Core actives

Glucosamine sulfate potassium, MSM, chondroitin sulfate sodium, L-aspartate calcium, boswellia extract, hydrolyzed type-II collagen, eggshell-membrane extract (10:1).

Clinical results

  • UC-II + MSM + boswellic acid (70-patient RCT, 6 mo, MRI): synovitis area improved 53.6%
  • Hydrolyzed type-II + MSM + chondroitin + glucosamine (98 patients, 8 wk): VAS pain −48.7%, WOMAC pain −53.4%, stiffness −51.0%, function −50.5%
  • Eggshell-membrane (NEM): fastest onset — pain −15.9% in 10 days

Featured product: OverTop Joint. PubMed-searchable; representative published findings.

Science that protects the lungs — restoring every breath 03
Lung Care
Science that protects the lungs — restoring every breath
Repairing the airway, strengthening defence, calming inflammation and restoring the essence of breathing through precision nutrition.
−24%Exacerbation risk
3.47×Symptom relief vs placebo
−32.8%Oxidative damage

Why it matters

The lungs are the core organ of gas exchange and immune defence. Per the WHO, more than 1 billion people live with chronic respiratory disease, with about 4.1 million deaths annually. Airway damage from air pollution and dust accounts for 37%; age-related oxidative decline affects over 62% of adults past 40.

Core mechanism

  • Mucosal-barrier repair — restores damaged airway epithelium and strengthens integrity.
  • Anti-oxidation & anti-inflammation — neutralises lung free radicals and curbs inflammatory factors.
  • Mucus clearance — thins mucus and promotes ciliary movement to clear metabolic waste.
  • Immune-defence strengthening — raises local immune-cell activity against harmful agents.

Core actives

NAC (N-acetylcysteine), curcumin, quercetin, bromelain.

Clinical results

  • NAC: acute-exacerbation risk −24% in COPD; −19% in chronic bronchitis / pre-COPD; symptom & quality-of-life improvement 3.47× placebo
  • Quercetin: oxidative stress −32.8%; upregulates airway-repair genes HOXB2 & ELF3
  • Quercetin + curcumin: 1-week viral clearance 72.0% vs 24.0% in mild-moderate COVID-19

Featured product: OverTop Lung Care. PANTHEON (Lancet Respiratory Medicine) and related trials.

Science that protects the liver — powering every metabolism 04
Liver Care
Science that protects the liver — powering every metabolism
Repairing hepatocytes, easing oxidative stress, regulating lipid metabolism and restoring liver vitality through precision nutrition.
−48.3%ALT
−45.7%AST
−32.1%Hepatic fat

Why it matters

The liver is the body's metabolic hub, running over 500 physiological functions. Per the Global Burden of Disease study, more than 1.5 billion people live with chronic liver disease; non-alcoholic fatty liver disease (NAFLD) prevalence reaches 25% globally and over 30% among Chinese adults.

Core mechanism

  • Membrane repair & stabilisation — replenishes essential phospholipids, restores membrane fluidity.
  • Antioxidant defence — raises glutathione, neutralises free radicals.
  • Lipid-metabolism regulation — reduces hepatic fat deposition, improves fatty-acid oxidation.
  • Anti-inflammation & detox support — enhances phase-II detox enzymes to clear harmful substances.

Core actives

Silybin (high bioavailability), curcumin, inosine, B-complex vitamins.

Clinical results

  • Silybin (300 mg/day, 12 wk): ALT −48.3%, AST −45.7%; hepatic fat content −32.1%
  • Curcumin (500 mg/day, 8 wk, NAFLD): ALT −39.6%, hepatic fat infiltration −28.9%
  • B-complex (12 wk): fatty-liver incidence −42.8%

Featured product: OverTop Liver Repair. Journal of Hepatology and related trials.

Accelerating the anti-aging breakthrough — rebuilding a younger life 05
Anti-Aging
Accelerating the anti-aging breakthrough — rebuilding a younger life
Cellular science and precision nutrition that bring younger-from-within possibility to every life stage.
+42.7%NAD+ level
+12.3%Telomere length
+35.2%Skin firmness

Why it matters

Aging shapes everyone's quality of life. First signs appear from 25; after 35 collagen loss and functional decline accelerate; past 45 cellular repair capacity drops sharply. AGX redefines youth through science — precise, safe and clinically verifiable at every stage.

Four age tracks

  • Light anti-aging (25–35) — targets dullness, oxidation, early lines, mild glycation.
  • Cellular revival (35–45) — restores cellular vitality, collagen, firmness and energy.
  • Deep cellular luxury (45+) — organ-level cellular renewal to reverse accumulated senescence.
  • Daily beauty — gentle daily collagen, antioxidant and radiance support.

Three core technologies

Cellular energy & mitochondrial repair (NAD+); collagen regeneration & structural firming; cellular autophagy & senescent-cell clearance.

Core actives & clinical results

  • NMN (1000 mg/day, 3 mo): NAD+ +42.7%, telomerase activity +38.9%, telomere length +12.3%
  • High-purity resveratrol (200 mg/day, 6 mo): telomerase +35.4%, ROS −35.8%, AGEs −29.4%
  • Pterostilbene (100 mg/day, 6 mo): telomerase +41.2%, telomere length +15.7%
  • High-bioavailability curcumin (800 mg/day): skin firmness +35.2%

Featured product: Gisbuer BeauTe Up. Nature Aging, Aging Cell and related trials.

Genomics & precision medical nutrition 06
Genomics
Genomics & precision medical nutrition
Decoding biological information, driving the evolution of life, shaping the health baseline.
WGSWhole-genome decoding
N=1Personalised intervention
AIVC™Validated in silico

Strategy

AGX bridges the translational gap between biological big-data and clinical nutritional intervention through high-throughput genomics fused with AI. Anchored by our core AIVC™ engine, we build a full-chain loop from multi-dimensional genomic prediction to targeted molecular intervention.

Clinical applications

  • Oncology genomics — deep sequencing of susceptibility loci and metabolic pathways for risk warning and chemo/radiotherapy nutritional support.
  • Metabolic health — analyses genetic polymorphism in drug and nutrient response for cardiovascular, diabetes and lipid disorders.
  • Genetic-expression control — pinpoints pathogenic and absorption loci for preventive medical nutrition.
  • Maternal & pediatric — monitors trace-element metabolism and immune-regulating genes across the reproductive cycle.
  • N=1 personalised intervention — integrates genome, phenotype and lifestyle for molecular-precision nutrition.

Vision

AGX is ending the era of descriptive testing and opening the era of programmable health — letting everyone foresee risk before it appears, and giving every protocol molecular-level precision.

Simulating your cells in a computer — rehearsing nutrition before it reaches you 07
AIVC™ Virtual Cell
Simulating your cells in a computer — rehearsing nutrition before it reaches you
AIVC builds a cross-dimensional digital twin of the cell, turning research from trial-and-error into predictive design.
10⁹/secSimulation frequency
100s×Faster R&D cycle
90%Experiments to go virtual

What is AIVC?

AIVC (AI Virtual Cell) is a foundational technology reshaping life-science research. In a supercomputer, AI simulates your cells — turning real cellular states, metabolic activity and nutrient responses into computable, predictable, verifiable digital models. You don't test on your own body: AIVC rehearses what each nutrient will do, then delivers only the optimal protocol.

Why we invest in AIVC

Biology has always lacked a programmable, inferable operating system. Traditional research is trapped in observe–hypothesise–verify cycles that cost years. With 10⁹ calculations per second covering the full metabolic path, R&D cycles compress hundreds of times — closing the loop from hypothesis to validation within the window a patient is waiting.

Core capability: simulate → predict → rehearse

  • Simulate — reconstructs key cellular features, fusing genome, proteome and metabolome into a digital twin.
  • Predict — infers nutrient impact on cellular state, outputting metabolic change, inflammation and aging markers.
  • Rehearse — models the full journey from intake to utilisation, from gut to organelle.

We deliver not an ordinary product, but a life-health reconstruction precisely simulated and repeatedly validated by AIVC virtual-cell technology.

Nutrition for every unyielding hope of life 08
Oncology Medical Nutrition
Nutrition for every unyielding hope of life
Stage-specific precision nutrition for post-operative recovery and chemo/radiotherapy support.
2Care scenarios
TargetedEnergy & immune support
MarrowProtection

Why it matters

On the cancer journey, nutrition is not an adjunct — it is a core force against disease. AGX brings together global oncology-nutrition and molecular-medicine teams, building precision mechanisms around the tumour micro-environment across two key scenarios.

① Post-operative stage

  • Anti-inflammation — calms local and systemic post-op inflammation, easing pain and swelling, speeding wound healing.
  • Anti-infection — strengthens resistance and lowers post-op infection rates.
  • Fast absorption + intestinal mucosa — easily absorbed nutrition that repairs gut mucosa and protects barrier function.
  • Raising white-blood-cells — supports marrow haematopoiesis to boost immune defence.

② Chemo / radiotherapy stage

  • High energy — high-protein, high-fat, low-carb balance to counter fatigue and wasting.
  • Strong immunity — activates immune cells and improves treatment tolerance.
  • Marrow protection — shields haematopoiesis and reduces myelosuppression.
  • Bone & muscle protection — limits bone loss and muscle atrophy to maintain quality of life.